2011
A field emerges
Foundational functional ultrasound work demonstrates brain activity mapping through sensitive blood-flow imaging.
Macé et al. · Nature MethodsA COLLECTIVE SCIENTIFIC JOURNEY
From a brain slice
in rodent to
human neuromonitoring
Functional ultrasound follows the brain’s hemodynamic response. From 2D maps to volumetric imaging, each advance opens another way to study brain function.
2015
Free to move
Urban and colleagues bring functional ultrasound to freely moving rats, connecting imaging with behavior.
Urban et al. · Nature Methods2020
Into the volume
Brain-wide volumetric fUS in awake mice extends the view from individual planes to three-dimensional activity.
Brunner et al. · Neuron2025
Link to neural activity
Connecting fUS blood-flow signals with neuronal firing, through work with Carandini and colleagues.
Núñez-Elizalde et al. · Neuron2026 — 2030
The next horizon
Open resources, larger-animal research and the pursuit of human applications shape the next questions.
A forward-looking research vision